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Clinical Studies on Shilajit

Updated: Apr 10

Shilajit was written about in the ancient Sushruta Samhita (600 BC), an ancient Ayurvedic text about medicine and surgery. Since then it has been praised as an amazing energy booster, health regulator, rejuvenator and magnifier of vitality. It has been used by Yogis, Ayurvedic Practitioners, Siberian Shamans, Olympic Athletes, and Clinical Doctors all the same. With it's vast array of nutrients and minerals does Shilajit really help with so many things in the body, and is it totally safe? We know it does from our hundreds of customers and our own experience, however the latest scientific research proves it as well! Here are some clinical studies to get you started on your research. Also check out this amazing article on Shilajit: https://www.ayurvedacollege.com/blog/shilajit/



The effects of Shilajit supplementation on fatigue-induced decreases in muscular strength and serum hydroxyproline levels

Joshua L. Keller, Terry J. Housh, Ethan C. Hill, Cory M. Smith, Richard J. Schmidt, Glen O. Johnson J Int Soc Sports Nutr. 2019; 16: 3. Published online 2019 Feb 6.

Conclusion: Shilajit supplementation elicited favorable muscle and connective tissue adaptation.

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364418/


The Human Skeletal Muscle Transcriptome in Response to Oral Shilajit Supplementation

Amitava Das, Soma Datta, Brian Rhea, Mithun Sinha, Muruganandam Veeraragavan, Gayle Gordillo, Sashwati Roy J Med Food. 2016 Jul 1

Conclusion: The current study reports for the first time that oral supplementation of Shilajit to overweight/class I obese human subjects resulted in skeletal muscle adaptation through upregulation of ECM-related genes that control muscle mechanotransduction properties, elasticity, repair, and regeneration.

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948208/


Evaluation of safety profile of black shilajit after 91 days repeated administration in rats

C Velmurugan, B Vivek, E Wilson, T Bharathi, T Sundaram Asian Pac J Trop Biomed. 2012 Mar

Conclusion: Long term Shilajit use did NOT show any toxicity or cause any adverse effects.

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609271/


Shilajit: A Natural Phytocomplex with Potential Procognitive Activity

Carlos Carrasco-Gallardo, Leonardo Guzmán, Ricardo B. Maccioni

Int J Alzheimers Dis. 2012; 2012

Conclusion: Shilajit is a potent and very safe dietary supplement, potentially able to prevent several diseases, but its main medical application now appears to come from its actions in benefit of cognition and potentially as a dietary supplement to prevent Alzheimer's disease. In essence, this is a nutraceutical product.

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296184/


Effect of Withinia Somnifera (Ashwagandha) and Shilajit on Alcohol Addiction in Mice

Priya Bansal, Sugato Banerjee Pharmacogn Mag. 2016 May; 12

Conclusion: These central nervous system active herbs alone or in combination reduced both alcohol dependence and withdrawal thus showing promising anti-addictive potential.

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4883068/


Complement-fixing Activity of Fulvic Acid from Shilajit and Other Natural Sources

Igor A. Schepetkin, Gang Xie, Mark A. Jutila, Mark T. Quinn Phytother Res. Author manuscript; available in PMC 2010 Mar 1

Conclusion: All Shilajit fractions exhibited dose-dependent complement-fixing (disposing of toxins and foreign substances in the body) activity in vitro with high potency. Furthermore, we found a strong correlation between complement-fixing activity and carboxylic group content in the Shilajit fractions and other FA sources. These data provide a molecular basis to explain at least part of the beneficial therapeutic properties of Shilajit and other humic extracts.

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2650748/


Efficacy of mummy on healing of pressure ulcers: A randomized controlled clinical trial on hospitalized patients in intensive care unit

Masoud Moghadari, Mozafar Rezvanipour, Mitra Mehrabani, Mehdi Ahmadinejad, Haleh Tajadini, Mohammad Hashem Hashempur Electron Physician. 2018 Jan;

Conclusion: The healing process was more prominent in the intervention group than the control group.

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853986/


The Effects of Shilajit on Brain Edema, Intracranial Pressure and Neurologic Outcomes following the Traumatic Brain Injury in Rat

Mohammad Khaksari, Reza Mahmmodi, Nader Shahrokhi, Mohammad Shabani, Siavash Joukar, Mobin Aqapour Iran J Basic Med Sci. 2013 Jul

Conclusion: The results of present study showed that Shilajit administration has neuroprotective effects in post-traumatic injuries through decreasing brain edema, blood-brain barrier permeability and ICP. Therefore, maybe through these mechanisms post-trauma neurologic score will be improved.

LInk: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3758058/


Shilajit: A panacea for high-altitude problems

Harsahay Meena, H. K. Pandey, M. C. Arya, Zakwan Ahmed Int J Ayurveda Res. 2010 Jan-Mar

Conclusion: It would certainly be helpful to fight against common high-altitude problems like hypoxia, AMS, HAPO, HACE, dehydration, UV radiation etc when taken as a supplement by people ascending to high altitudes. In light of Shilajit's tremendous medicinal potential, it would not be an exaggeration to say that it can be a panacea for all human ailments and Nature's wonderful gift to mankind.

Link: https://www.ncbi.nlm.nih.gov/pmc


Protective effect of Mumiju (Shilajit) against acetic acid-induced ulcerative colitis in rats

Nadar Shahrokhi, Zakieh Keshavarzi, Mohammad Khaksari Haddad, Fereshteh Amirafzali, Shahriar Dabiri, Nava Shahrokhi Avicenna J Phytomed. 2018 Sep-Oct

Conclusion: The present investigation demonstrates that Mumiju (Shilajit) could be regarded as a herb with potent therapeutic value in the amelioration of experimental colitis in laboratory animals by modulation of oxidant- antioxidant system.


Clinical evaluation of purified Shilajit on testosterone levels in healthy volunteers.

Pandit S, Biswas S, Jana U, De RK, Mukhopadhyay SC, Biswas TK. Andrologia. 2016 Jun

Conclusion: Treatment with Shilajit for consecutive 90 days revealed that it has significantly (P < 0.05) increased total testosterone, free testosterone and dehydroepiandrosterone (DHEAS) compared with placebo. Gonadotropic hormones (LH and FSH) levels were well maintained.

Link: https://www.ncbi.nlm.nih.gov/pubmed/26395129






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